Timeline of Discovery
Breakthrough Cancer Research was launched in 2012 but our history goes back to the mid 90’s when our founder Professor Gerry O’Sullivan, spurred on by the unmet needs of his patients, set up a small research group in the Mercy Hospital, Cork. From these humble beginnings began a vision of patient focused research, tackling poorer prognosis cancers. This timeline is a tiny snapshot of what has been achieved as part of an exceptional community of cancer research, clinicians and patients and the generous support of the public.
2023
CUSTOM FIT
World first project creating bespoke breast prostheses for women post-mastectomy. ‘The ability to...
World first project creating bespoke breast prostheses for women post-mastectomy. ‘The ability to provide bespoke prostheses, regardless of shape and size, to perfectly match the residual breast is a significant improvement over the current standard of care for women who have undergone a mastectomy.’ ‘There is a need for a renewed focus on quality of life and the application of user-centric design to develop innovative solutions for these patients. We have an incredibly talented PhD researcher, EmmaJude Lyons, who is funded by Breakthrough Cancer Research, who has taken this project from concept to advanced prototypes in a few short months,’
2023
FIRST ALL IRELAND CANCER NETWORK
First All-Ireland Cancer Network, AllCaN established to support and facilitate knowledge sharing ...
First All-Ireland Cancer Network, AllCaN established to support and facilitate knowledge sharing between exemplary teams in institutions across the island of Ireland, who are taking on less survivable cancers. The successful awardee will receive a €1 million investment for researchers, clinicians, patients, and industry to work together to significantly improve survival rates. The first of these AllCaN Grants focuses on oesophageal cancer to improve early detection and outcomes for patients with, or at risk of, developing the disease.
Read more here:
2022
MAKING MORE SURVIVORS
An additional €2 million injection in research funding to find urgent new treatments and improve ...
An additional €2 million injection in research funding to find urgent new treatments and improve early detection for Ireland’s seven most lethal cancers. The funding, which will be allocated to researchers immediately and over the coming six months, was revealed in the Irish medical research charity’s new 5-year research strategy ‘Making More Survivors’. This strategy highlights Breakthrough’s vision to create 100% survival for 100% of cancers by investing more research funding into the cancers that need the greatest improvement, those that cause the most deaths, and by reducing the time it takes for lab discoveries to get to patients. Read more here.
2022
A PERSONAL APPROACH
New cancer research funded by Breakthrough as part of New Clinical Cancer Fellowship in Cork will...
New cancer research funded by Breakthrough as part of New Clinical Cancer Fellowship in Cork will help individualise treatment for patients with early-stage breast cancer to improve survival
2022
OVERCOMING THE RESISTANCE
Trial of new Lithium enhanced Chemotherapy enrolls its first patients. The finding of this combin...
Trial of new Lithium enhanced Chemotherapy enrolls its first patients. The finding of this combination came from a discovery of how cancer cells use a process called Autophagy (Self -Eating) to repair and recycle damage caused by chemo, allowing the cells to recover. Lithium blocks the cells’ ability to recover.
2021
NATURAL KILLERS
Breakthrough funded research shows how fractalkine pulls natural killer cells into belly fat prev...
Breakthrough funded research shows how fractalkine pulls natural killer cells into belly fat preventing them from reaching oesophageal tumour.
2020
SHOP THAT NEARLY WASN'T
We deliver a world first in 2020 – The Shop That Nearly Wasn’t – a shop entirely stocked a...
We deliver a world first in 2020 – The Shop That Nearly Wasn’t – a shop entirely stocked and staffed by survivors of cancer and a showcase of talent that we would have lost if it weren’t for research.
2020
WAITING TO EXHALE
Breakthrough supports a new research project investigating the potential of breath droplets to de...
Breakthrough supports a new research project investigating the potential of breath droplets to detect mutations in early stage lung cancer.
2019
ENDOWED CHAIR
Professor Roisin M. Connolly appointed to Professor Gerald O’Sullivan Chair In Cancer Research to...
Professor Roisin M. Connolly appointed to Professor Gerald O’Sullivan Chair In Cancer Research to lead cancer research in South West Region.
2019
BREAKING THROUGH
In September 2019 we hosted a conference in Cork to celebrate 20 years of Translational Research ...
In September 2019 we hosted a conference in Cork to celebrate 20 years of Translational Research in the region. With a stellar panel of international and local speakers, the themes included, Survivorship, Autophagy and Metabolism in Cancer, Re-Thinking the Tumour Microenvironment: Immune and Microbial Influences, Innovative Technologies for Delivery of Cancer Therapeutics, Patient Trials: Transforming Practice.
2019
PARTNERING UP
We award our first Musgrave PhD Scholarship in Trinity College Dublin to Fiona O’Connell fo...
We award our first Musgrave PhD Scholarship in Trinity College Dublin to Fiona O’Connell for a project looking at how obesity effects the response of the immune system by looking at how adipose (fat) tissue taken from obese and non-obese patients effects how different cells from the immune system grow and work. Her project will then look at whether healthy dietary fats effect how the immune system responds to radiation treatment and if these fats could be used to change that response.
2018
PHASE 2
Colorectal Trial of Endo-Ve device moves to Phase 2
2018
FIVE FOR THE FIGHT
A new Cancer Immunology Fellowship is launched in partnership with Qualtrics & Five for the F...
A new Cancer Immunology Fellowship is launched in partnership with Qualtrics & Five for the Fight, names in memory of their late colleague and leader Dermot Costello.
2017
SCOPE FOR NEW TREATMENT
Phase one oesophageal trial opens for Endo-Ve device.
2016
SYNERGY
New trial for Malignant Melanoma combining Electrochemotherapy and Immunotherapy opens
2015
GERM WARFARE
Breakthrough-funded researchers are the first in the world to show that the bacteria in your body...
Breakthrough-funded researchers are the first in the world to show that the bacteria in your body can both positively and negatively affect cancer treatment.
2015
HOME SWEET HOME
Research Labs move to new purpose built centre within to join other health research groups in a n...
Research Labs move to new purpose built centre within to join other health research groups in a new Translational Health Campus in UCC’s Western Gateway Building.
2015
BREATHING SPACE
The first patient is safely treated with Thora-Ve device for inoperable lung cancer
2014
FIRST TIME
First proposal of the existence of a Tumour Microbiome.
2014
HOPE GROWS
A Breakthrough supported clinical trial for inoperable colorectal cancers expands into three Iris...
A Breakthrough supported clinical trial for inoperable colorectal cancers expands into three Irish hospitals and from Ireland into Denmark.
2013
CHANGE GANG
CCRC researchers receive the 2013 Pfizer Innovation through team work award for their device to t...
CCRC researchers receive the 2013 Pfizer Innovation through team work award for their device to treat inoperable lung cancer.
2012
A PROMISE FOR THE FUTURE
Dr. Mark Tangney’s work using bacteria to deliver anti-cancer treatment is selected in 2012...
Dr. Mark Tangney’s work using bacteria to deliver anti-cancer treatment is selected in 2012 by the prestigious journal, New Scientist, as one of the 5 most promising approaches to end cancer in the next 10 years.
2012
A STRONG FOUNDATION
Our founder Prof. Gerry O’Sullivan passed away in 2012 but left behind the legacy of a stro...
Our founder Prof. Gerry O’Sullivan passed away in 2012 but left behind the legacy of a strong research vision and team. “He laid an incredibly strong foundation and on that foundation great things are being built.” Dr. Derek Power.
2012
BREAKTHROUGH
Our national charity Breakthrough Cancer Research is launched, allowing us to take our message of...
Our national charity Breakthrough Cancer Research is launched, allowing us to take our message of hope all around Ireland.
2010
A NOBLE PURSUIT
In 2010, while visiting our research teams, Nobel prize winner James Watson says about the centre...
In 2010, while visiting our research teams, Nobel prize winner James Watson says about the centre’s Autophagy programme; “You’re ahead of us over here. This is incredible, I can’t wait to tell them about this back home.”
2009
LET'S TALK TREATMENT
Helped host the 10th Annual Meeting of the International Society for Cell and Gene Therapy of Can...
Helped host the 10th Annual Meeting of the International Society for Cell and Gene Therapy of Cancer, bringing world-class experts together to share their findings. “Right now a revolutionary in biology and medicine is occurring. New miraculous techniques are being built and developed for treatment of cancer based on our deep understanding of what is wrong with the cancer cell.….I wasn’t prepared for the magnitude of the excellence and the depth of the expertise that’s here in the Cork Cancer Centre.” Prof Albert Deisseroth, Food and Drug Administration – USA and former President of the Sydney Kimmel Cancer Centre
2009
NEW HOPE
In 2009, CCRC receives IMB approval to commence clinical trial for treatment of inoperable colore...
In 2009, CCRC receives IMB approval to commence clinical trial for treatment of inoperable colorectal tumours using their patented device for both drug and gene delivery.
2009
EUROPE CALLING
Founder Prof. Gerald C. O’Sullivan commences Presidency of the European Surgical Association.
Founder Prof. Gerald C. O’Sullivan commences Presidency of the European Surgical Association.
2009
PROSTATE CANCER VACCINE
A gene therapy approach is shown to reduce prostate tumour growth and is published by CCRC in Mol...
A gene therapy approach is shown to reduce prostate tumour growth and is published by CCRC in Molecular Therapy.
2008
PROFOUND IMPACT
In recognition of his “profound impact on Irish, European, and American surgery”, the American Co...
In recognition of his “profound impact on Irish, European, and American surgery”, the American College of Surgeons confers an Honorary Fellowship on Centre Director Prof. Gerald C. O’Sullivan.
2007
IT'S A FIRST
Irish Medicines Board’s (IMB) approval to commence the first clinical trial in Ireland using gene...
Irish Medicines Board’s (IMB) approval to commence the first clinical trial in Ireland using gene delivery.
2006
IN THE BLOOD
Leukaemia research published in Blood – One of the Top 100 influential Biology and Medical Journa...
Leukaemia research published in Blood – One of the Top 100 influential Biology and Medical Journals.
2006
ELECTED
Our Founder Prof. Gerald C. O’Sullivan is elected President of the Royal College of Surgeons in I...
Our Founder Prof. Gerald C. O’Sullivan is elected President of the Royal College of Surgeons in Ireland.
2004
MOVING ON UP
Translational Research moves to the Leslie C. Quick Jr. Laboratory, within the Biosciences Instit...
Translational Research moves to the Leslie C. Quick Jr. Laboratory, within the Biosciences Institute, UCC with significant expansion in programmes and personnel.
2004
UNDER MY SKIN
Only Irish Site for ESOPE commences with a clinical study using Electrochemotherapy to treat ino...
Only Irish Site for ESOPE commences with a clinical study using Electrochemotherapy to treat inoperable skin based cancer, melanoma and recurrent breast cancer. The combined EU study results show an 85% response rate to the treatment.
2003
HIGH ALERT
Cork commences a colorectal screening clinic, the first in Ireland, to screen high risk patients....
Cork commences a colorectal screening clinic, the first in Ireland, to screen high risk patients. The clinic also gives opportunity to research diet and lifestyle influences.
2000
A NATURAL REACTION
First group in the world to link immune reactivity and cancer survival publishing in Nature Medic...
First group in the world to link immune reactivity and cancer survival publishing in Nature Medicine – the premier journal for biomedical research.
1999
Cork Cancer Research
In 1999 Cork Cancer Research Centre was formed with support from Atlantic Philanthropies and Iris...
In 1999 Cork Cancer Research Centre was formed with support from Atlantic Philanthropies and Irish Government funding to create a foundation structure to link clinicians working in the Cork Hospitals with researchers working in University College Cork.
1995
CRAM
In 1995 Professor Gerry O’Sullivan, spurred on by the unmet needs of his patients and his own bel...
In 1995 Professor Gerry O’Sullivan, spurred on by the unmet needs of his patients and his own belief in research, set up a small research group in the Mercy Hospital in Cork called CRAM – Cancer Research at Mercy Hospital. Starting in a small basement disused pathology lab, from these humble beginnings began a vision of research, to focus on the secondary spread of cancer and poorer prognosis cancers.