Breakthrough Cancer Research is a leading Irish medical research charity funding game-changing cancer research.

This year we are funding world-class research projects to develop new ways to treat cancer, to improve quality of life for people with cancer, to improve treatment outcomes, and ultimately – to save more lives.

9,000 Irish men, women and children women still lose their life to cancer every year. But with your continued support, our researchers are determined to dramatically reduce this number.

Together we will save the people who cannot be saved today.

  • All
  • Detection
  • Policy
  • Prevention
  • Survivorship
  • Treatment
It’s in the blood! – Catching ovarian cancer early with lo
Hepato-ProMet: Proteomic assay of metabolic progression from steatosis
Investigating the Role of TRPA1 in Lung Cancer
Development and Modelling of a Non-Specific Symptoms (NSS) Cancer Refe
NAMCAM: New Approach Methodologies (NAMs) for Assessing Cancer Advance
Digital Interventions Against Cancer Misinformation
Innovative Clinical interventions for Uveal Melanoma -Developing Novel
ARMOR: tAilored peRsonalised Medicine fOr gastric canceR
Predicting Patient Outcomes in Pancreatic Cancer via Multiomic Analysi
Development of a Personalised Near Patient (PNP) Allogeneic NK-Cell Im
OvaLoad: Enhanced targeted treatments for ovarian cancer
Modulation Of carbon Nanoparticles for pAncReatic Cancer tHerapy (MONA
TIME IS NOW: A qualiTatIve, Multi-pErspectIval Study on the pheNomenon
Early Detection of Epithelial Ovarian Cancer using Next Generation Bio
Evaluating Barrett’s and Dysplasia incidence and treatment trends acro
Investigating the role of complement in predicting and modulating trea
Identification of functional sites of mechanotransduction on syndecan-
Lnc-ing ZEB to non-coding RNAs: an alternative path to drug resistance
HERO: Targeting HER2 in Ovarian cancer
Understanding the impact of palliative and ablative radiotherapy on He
Targeting AMPA receptors in brain tumour related epilepsy: a precision
Information and communication needs in lung cancer: A qualitative anal
Peri-Operative Exercise and Nutrition Optimisation (PANO) Trial in Per
The impact of cellular metabolic pathway manipulation on inflammatory-
Pharmacoepidemiology research to determine modifiable risk factors ass
Age inequalities in Barrett’s oesophagus and oesophageal adenocarcinom
Understanding the patterns and barriers of physical activity among peo
Environmental exposures and oesophageal cancer incidence on the island
Role of intrinsic immune checkpoint signalling pre-malignant Barret’s
Malignant Potential of Barrett’s Oesophagus: Morphomolecular Pathology
Novel approaches to activating the immune system in colorectal cancer
All-Ireland Cancer Network (AllCaN) – Oesophageal Cancer
Exploring Barriers and Enablers to the Implementation of Novel Capsule
Investigation of IRE1α contribution to stromal-natural killer cell cro
Advanced Cancer Care: Enhancing Systems and Structures to Deliver In-H
Investigating the effect of calcium electroporation on the inflammator
Characterising the Anti-Tumour Capacity of Immune Cells Targeting Glio
Investigation of a new targeted cancer drug delivery system – Ca
Circular RNA as a blood biomarker for ovarian cancer
Using a phospho-proteomic Strategy to identify druggable targets in hi
Discovery of novel long non coding RNAs for early detection and monito
Design of Carbon based nanoplatform to Target pancreatic cancer
Multiparametric analysis of the pancreatic cancer microenvironment in
Investigating the Therapeutic and Prognostic Utility of Long Non-Codin
The Functions of Voltage-Gated Calcium Channels in Oesophageal Adenoca
Identifying Novel Druggable Targets in High Grade Serous Ovarian Cance
Investigating Minimal Residual Disease Post-Operatively in Patients wi
Identification of ISG15 modified autophagy proteins and their potentia
Surgery, radiotherapy, chemotherapy, but now what? Exploring the rehab
Identification of Methods to Predict Women’s response to Breast
Accelerating The Route Towards Metastatic Uveal Melanoma Diagnosis And
The Role & Standardisation of Expanded Access Chemotherapy Progra
Investigating Novel Therapeutic Vulnerabilities to Target High-Risk Mu
Developing a non-rodent xenograft model of Multiple Myeloma and its us
Women’s Cancer Survivorship: Supporting and Innovating for Change: Die
Investigation into the mechanism by which post-translational modificat
How can we build in-vitro models of lung cancer that effectively mimic
Can synthetic miR-31 mimics/anti-miRs be employed as a novel therapeut
A Longitudinal, Mixed Methods Study Investigating Resilience, Social S
Exploring the impact and expression of pre-treatment Cancer Related Co
Therapeutically remodelling the immune profile of ‘cold’ tumours in ob
To investigate the effects of endogenous ligands on Vitamin D receptor
Effect of a pre- and post-operative exercise programme versus standard
Peri-operative Exercise and Nutrition Optimisation (PANO) Trial
Targeting platinum-resistant disease in Ovarian Cancer
Cysteinyl Leukotriene Receptor Signalling: Novel therapeutic targets t
The impacts of Covid-19 on cancer patients and survivors from a social
Identification of therapeutically relevant tumour-associated alteratio
Investigating the value of detecting subclinical lymphoedema among can
Boosting oxygen diffusion in the radioresistant Oesophageal tumour mi
Investigating the protein MUC1 and its potential role in using the tu
Towards improved immunotherapy: Investigating the effects of Pyrazinib
Investigating the molecular mechanisms of altered NCAPG expression in
Improving radiation resistance in oesophageal cancer using a novel the
Investigation into the role of autophagy in differentiation in leukaem
A Correlative Assessment of the role of Stroma Mechanics in Pancreatic
Patients’ Access to Advanced Cancer Therapies: Ethics and Equity of Ac
Utilising proteomics-derived data in establishing predictive biomarker
Estimating Costs, Resource Use and Financial Toxicity Amongst Cancer P
Examination of the Effects of Acid-Exposure on Oesophageal-Cancer Cell
Making a blood/urine DNA test for ovarian cancer
Use of 3D printing in the design and manufacture of bespoke prosthesis
Using an immune-based strategy to target Ovarian Cancer
Regulation of long, non-coding RNAs in ovarian cancer by the tumour su
Getting a Handle on Non-Canonical Polycomb Repressor Complex 1 (nc-PRC
Investigation of novel drugs in Chemotherapy-resistant Ovarian Cancer
Comparison of detection methods for minimal residual disease in multip
The utility of exhaled breath condensate to detect sub-clonal mutation
Scoping Research for a Digital Platform Connecting Irish Cancer Inform
Breakthrough Cancer Research Nutrition
Targeting the anti-apoptotic BCL-2 dependence in Multiple Myeloma
Assess immune response to neoadjuvant treatment in oesophagogastric ad
Acid-stimulated Ca2+ signals as a potential therapeutic target for the
Investigation of the role of cysteinyl leukotriene (CysLT) receptors i
Women’s Cancer Survivorship: Supporting and Innovating for Change
Evaluation of Electrochemotherapy to Improve Patient Quality of Life a
Evaluating anti-neoplastic activity of HDAC6 inhibitors in uveal melan
Evaluation of the Therapeutic and Adverse Potential Cannabinoids in vi
Living and Dying Well – An Investigation of the Psychosocial and Spiri
Involving Men with PROstate cancer in Engaged Research
Measuring genetic markers in the blood of patients with small cell lun
Investigation of new biomarkers of treatment response in glioblastoma
Precision Oncology Ireland
Effect of bacterial membrane vesicles (BMVs) released by human gut mic
Investigating chemotherapy-resistant ovarian cancer
Epigenetic modulating compounds as potential therapeutic agents for oe
Effect of a novel drug and electroporation on melanoma and intratumour
Harnessing the power of the immune system to fight obesity associated
Epigenetic modulating compounds as potential adjunct therapeutic agent
Radiation Response in Oesophageal Cancer: the role of visceral fat tis
Role of regulatory B cells in response to immunotherapy in advance can
Electroporation for Skin Cancer Treatment
Investigation into the role of autophagy in the recurrence of Ovarian
GOLD-DRUG IN OESOPHAGEAL CANCER
Evaluation of the impact of emotional, nutritional and physical exerci
Gold-drug: Targeting a novel dual inhibitor drug with gold nanoparticl
Evaluation of a Mindfulness Based Stress Reduction programme on the qu
Evaluation of the role of MxA and ISGylation in chemosensitivity in oe
Combining electrochemotherapy with a Toll Like receptor agonist for th
Contribution of diet and lifestyle factors and metabolic phenotype to
Nutrition and cancer: what is the information experience?
Enhancing electroporation delivery for pancreatic cancer
Osteosarcoma Combination of Electroporation of Metabolic Modulators wi
Bacteria in Human Tumours
Ovarian Research Fellowship Announced
Precision Oncology Ireland
Infrastructure grant: LI-COR Odessey CLx Infra red Imaging system
Role of Autophagy in Differentiation Therapy in Acute Myeloid Leukaemi
Role of Autophagy in Progression of Oesophageal Cancer
The role of diet, nutritional assessment and intervention in the preve
Investigator Led Trials on the Horizon for Pancreatic Cancer
Infrastructure Grant: Cold Plate for Tissue Microtomy

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