Research
Priorities

Breakthrough Cancer Research is a leading Irish medical research charity funding game-changing cancer research.

This year we are funding world-class research projects to develop new ways to treat cancer, to improve quality of life for people with cancer, to improve treatment outcomes, and ultimately – to save more lives.

9,000 Irish men, women and children women still lose their life to cancer every year. But with your continued support, our researchers are determined to dramatically reduce this number.

Together we will save the people who cannot be saved today.

  • All
  • Detection
  • Policy
  • Prevention
  • Survivorship
  • Treatment
Therapeutically remodelling the immune profile of ‘cold’ tumours in ob
Surgery, radiotherapy, chemotherapy, but now what? Exploring the rehab
PreCog: Exploring the impact and expression of pre-treatment Cancer Re
A Longitudinal, Mixed Methods Study Investigating Resilience, Social S
Investigation into the mechanism by which post-translational modificat
Development of carbon based nano – platform for cancer therapy 
Accelerating The Route Towards Metastatic Uveal Melanoma Diagnosis And
To investigate the effects of endogenous ligands on Vitamin D receptor
Follow up study on the effect of a pre- and post-operative exercise pr
Peri-operative Exercise and Nutrition Optimisation (PANO) Trial
The Role & Standardisation of Expanded Access Chemotherapy Progra
Investigating Novel Therapeutic Vulnerabilities to Target High-Risk Mu
Targeting platinum-resistant disease in Ovarian Cancer
Cysteinyl Leukotriene Receptor Signalling: Novel therapeutic targets t
Identification of therapeutically relevant tumour-associated alteratio
Comparison of detection methods for minimal residual disease in multip
Investigating the value of detecting subclinical lymphoedema among can
Boosting oxygen diffusion in the radioresistant Oesophageal tumour mi
Examination of the Effects of Acid-Exposure on Oesophageal-Cancer Cell
Investigating the protein MUC1 and it’s potential role in using the t
Making a blood/urine DNA test for ovarian cancer
Towards improved immunotherapy: Investigating the effects of Pyrazinib
Use of 3D printing in the design and manufacture of bespoke sealing de
Investigating the molecular mechanisms of altered NCAPG expression in
Using an immune-based strategy to target Ovarian Cancer
Regulation of long, non-coding RNAs in ovarian cancer by the tumour su
Improving radiation resistance in oesophageal cancer using a novel the
Investigation into the role of autophagy in differentiation in leukaem
A Correlative Assessment of the role of Stroma Mechanics in Pancreatic
GOLD-DRUG IN OESOPHAGEAL CANCER
Estimating Costs, Resource Use and Financial Toxicity Amongst Cancer P
Utilising proteomics-derived data in establishing predictive biomarker
Patients’ Access to Advanced Cancer Therapies: Ethics and Equity of Ac
Investigation of novel drugs in Chemotherapy-resistant Ovarian Cancer
Getting a Handle on Non-Canonical Polycomb Repressor Complex 1 (nc-PRC
The utility of exhaled breath condensate to detect sub-clonal mutation
Scoping Research for a Digital Platform Connecting Irish Cancer Inform
Breakthrough Cancer Nutrition
Targeting the anti-apoptotic BCL-2 dependence in Multiple Myeloma
Assess immune response to neoadjuvant treatment in oesophagogastric ad
Acid-stimulated Ca2+ signals as a potential therapeutic target for the
Investigation of the role of cysteinyl leukotriene (CysLT) receptors i
Women’s Cancer Survivorship: Supporting and Innovating for Change
Evaluation of Electrochemotherapy to Improve Patient Quality of Life a
Evaluating anti-neoplastic activity of HDAC6 inhibitors in uveal melan
Evaluation of the Therapeutic and Adverse Potential Cannabinoids in vi
Precision Oncology Ireland
Infrastructure grant: LI-COR Odessey CLx Infra red Imaging system
Living and Dying Well – An Investigation of the Psychosocial and Spiri
The EVeCanS Study
Osteosarcoma Combination of Electroporation of Metabolic Modulators wi
Epigenetic modulating compounds as potential therapeutic agents for oe
Role of Autophagy in Differentiation Therapy in AML
Role of Autophagy in Progression of Oesophageal Cancer
The role of diet, nutritional assessment and intervention in the preve
Bacteria in Human Tumours
Ovarian Research Fellowship Announced
Gold-drug: Targeting a novel dual inhibitor drug with gold nanoparticl
Evaluation of a Mindfulness Based Stress Reduction programme on the qu
Evaluation of the role of MxA and ISGylation in chemosensitivity in oe
Combining electrochemotherapy with a Toll Like receptor agonist for th
Contribution of diet and lifestyle factors and metabolic phenotype to
Nutrition and cancer: what is the information experience?
Enhancing electroporation delivery for pancreatic cancer
Effect of a novel drug and electroporation on melanoma and intratumour
Harnessing the power of the immune system to fight obesity associated
Epigenetic modulating compounds as potential adjunct therapeutic agent
Involving Men with PROstate cancer in Engaged Research
Radiation Response in Oesophageal Cancer: the role of visceral fat tis
Role of regulatory B cells in response to immunotherapy in advance can
Investigator Led Trials on the Horizon for Pancreatic Cancer
Infrastructure Grant: Cold Plate for Tissue Microtomy
Electroporation for Skin Cancer Treatment
Investigation into the role of autophagy in the recurrence of Ovarian
Measuring genetic markers in the blood of patients with small cell lun
Investigation of new biomarkers of treatment response in glioblastoma
Precision Oncology Ireland
Effect of bacterial membrane vesicles (BMVs) released by human gut mic
Investigating chemotherapy-resistant ovarian cancer

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